Leon Medica's name appears on over 90 albums and 10 movies. He received an American Music Award in 1989 for producing Doobie Brother Tom Johnston's "Where Are You Tonight?" on the Dirty Dancing movie and the over 37 million-selling soundtrack, a 1998 Grammy for his participation as manager of Anders Osborne on Keb Mo's Slow Down album, the 1989 Times Music Award for Best Bassist, and Gambit Magazine’s Song of the Century Award in 1999 for "New Orleans Ladies." Leon received a Letter of Appreciation from President Ronald Reagan, five USO Certificates of Appreciation, six DOD Certificates of Esteem, a Louisiana Music Association Lifetime Achievement Award, and is in the Louisiana Music Hall of Fame.

Leon received a Grammy nomination in January, 2007, for his work on Tab Benoit's Brother to the Blues album. Tab's follow-up album, Power of the Pontchartrain, also with members of LeRoux, was in the top 5 on Billboard's Blues chart for over 15 weeks. LeRoux recently recorded a live double album and DVD, Night Train to Nashville, with Tab Benoit, Jimmy Hall, Kim Wilson, Jim Lauderdale, Jeff Hanna, Waylon Thibodeaux, and Johnny Sansone, which has been released and ranks #1 on Billboard's Blues chart. Leon and members of LeRoux continue to headline concerts and are on tour with Tab Benoit throughout the US, Canada, and the Caribbean.

Medica’s musical journey began in the mid-1960s in Alexandria, LA. His first musical experiences were playing clubs and fraternity parties at LSU in Baton Rouge. As he became more proficient on the bass, he had the opportunity to record with such blues greats as Silos Hogan, Whispering Smith, Henry Gray, and other great Baton Rouge blues artists. By the end of the '60s, his bands opened for Strawberry Alarm Clock, The Who, and Creedence Clearwater Revival. The decade was highlighted by a performance at the New Orleans International Pop Festival and playing in Chuck Berry’s band at the Festival of Man & Earth.

His first major break came in 1972 when he performed music and acted on Broadway in New York in "Earl of Ruston." That was followed by four months of performing in London, England and a year in the Off-Broadway hit "Iphiginia" starring Tommy Lee Jones. After moving back to Baton Rouge, he recorded and toured with the band Potliquor. A production company in Denver contacted Medica to become part of a studio band, and he jumped at the opportunity to improve his studio bass chops and production skills. He returned to Bogalusa, Louisiana’s Studio in the County, recording with such greats as Clifton Chenier, Gatemouth Brown, Betty Davis (Miles Davis' wife), and the French superstar Dick Rivers. This was also the time that Medica co-wrote "New Orleans Ladies" and the band Louisiana’s LeRoux was formed.

After touring the United States and Africa with Gatemouth Brown, LeRoux signed with Capitol Records. From 1977 through 1983, Medica produced and wrote songs for four of the five LeRoux albums, and did numerous tours and many TV performances including Solid Gold, Midnight Special, and Don Kirshner’s Rock Concert. At the same time, he began writing and producing songs for movies.

From 1984 through 1988, he was asked to join the USO All-Star band to perform overseas for one month each year. Leon, along with Phil Ehart and other members of Kansas, Tom Johnston and Pat Simmons of The Doobie Brothers, Steve Morris, Steven Stills, members from Cheap Trick, Pablo Cruise, and Santana, formed the First Airborne Rock & Roll Band and toured over twenty foreign countries over that four-year period. On one overseas USO tour, he acted as tour manager for Randy Travis and Patty Loveless. In that same time period, he also gave his time and talent to five Music & Tennis tournaments with pro tennis players and celebrity musicians that raised over $1 million for the National Academy of Recording Arts & Sciences, Inc. (NARAS) educational fund.

From 1987 through 1989, Leon recorded and performed with Cajun rocker Zachary Richard, touring the US, Canada, and Europe many times. One of Medica’s biggest achievements was producing Tom Johnston of The Doobie Brothers on the multi-platinum "Dirty Dancing" Soundtrack, one of the biggest-selling soundtracks of all time.

Throughout the '90s and to the present day he continues writing, producing, and doing studio work. Adding his bass chops to recordings with Country artist Vern Gosden and R&B’s Maurice Williams are among his numerous credits. He started a management company, securing recording and publishing agreements for Audra and Alayna on Sony. He also managed and produced Grammy-winning Anders Osborn on Sony/Epic and Brian McComas on Disney’s Lyric Street Records. He toured Europe for one last time with his old friend, the late Gatemouth Brown.

Leon endorses Analysis Plus cables, Peavey Electronics, Category 5 amps, and PreSonus.